SB239063

  • Catalog number
    B1699-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    SB239063; SB-239063; SB239063; trans-4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]-cyclohexanol; 4-(4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)cyclohexanol; 4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazol-1-yl]cyclohexan-1-ol
  • Description
    SB239063 is a potent and selective p38 MAPK inhibitor with an IC50 of 44 nM against p38α MAPK while exhibited no activity against the γ- and δ-kinase isoforms.
  • CAS Number
    193551-21-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₀H₂₁FN₄O₂
  • Molecular Weight
    368.4
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective p38 MAPK inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD03792786
  • PubChem CID
    5166
  • SMILES
    COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
  • InChi
    InChI=1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3
  • InChi Key
    ZQUSFAUAYSEREK-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    SB239063
  • Alternative name
    SB239063
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