SB239063
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Catalog numberB1699-5
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PricePlease ask
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Size5 mg
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Alternative_nameSB239063; SB-239063; SB239063; trans-4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]-cyclohexanol; 4-(4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)cyclohexanol; 4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazol-1-yl]cyclohexan-1-ol
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DescriptionSB239063 is a potent and selective p38 MAPK inhibitor with an IC50 of 44 nM against p38α MAPK while exhibited no activity against the γ- and δ-kinase isoforms.
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CAS Number193551-21-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₀H₂₁FN₄O₂
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Molecular Weight368.4
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent and selective p38 MAPK inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD03792786
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PubChem CID5166
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SMILESCOC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
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InChiInChI=1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3
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InChi KeyZQUSFAUAYSEREK-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameSB239063
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Alternative nameSB239063
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