Bromosporine

• Catalog number
  2652-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  Ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
• Description
  Bromosporine is a broad spectrum bromodomain inhibitor (IC₅₀s = 0.41 µM, 0.29 µM, 0.122 µM and 0.017 µM for BRD2, BRD4, BRD9 and CECR2, respectively). At 1 µM, Bromosporine accelerates FRAP recovery of BRD4 and CREBBP, while displaying no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 µM.
• CAS Number
  1619994-69-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₂₀N₆O₄S
• Molecular Weight
  404.44
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~35 mg/ml) or EtOH (~ 10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A bromodomain family inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  O=C(OCC)NC1=CC(C2=CC=C(C)C(NS(=O)(C)=O)=C2)=NN3C1=NN=C3C
• InChi
  InChI=1S/C17H20N6O4S/c1-5-27-17(24)18-15-9-14(21-23-11(3)19-20-16(15)23)12-7-6-10(2)13(8-12)22-28(4,25)26/h6-9,22H,5H2,1-4H3,(H,18,24)
• InChi Key
  UYBRROMMFMPJAN-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Bromosporine  
• Short name
  Bromosporine
• Alternative name
  Bromosporine

Similar products