anti- PKC beta antibody
-
Catalog numberFNab06481
-
PricePlease ask
-
Size2X100μg
-
-
Formliquid
-
PurificationImmunogen affinity purified
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
BackgroundProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
-
Immunogenprotein kinase C, beta
-
SynonymsPKC B, PKC beta, PKCB, PRKCB, PRKCB1, PRKCB2, Protein kinase C beta type, protein kinase C, beta
-
Calculated MWRefer to figures
-
Uniprot IDP05771
-
SpecificityMouse
-
Tested ApplicationELISA, WB, IHC
-
Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200
-
Image1Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06481(PRKCB antibody) at dilution of 1:50
-
Image4mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06481(PRKCB antibody) at dilution of 1:1000
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolPRKCH, PRKD1, PRRT2, PRKDC
-
Short nameanti- PKC beta antibody
-
TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
-
HostRabbit
-
IsotypeIgG
-
Alternative nameantibody to- PKC b (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameprotein kinase C eta
-
Synonyms gene
-
Synonyms gene name
- protein kinase C, eta
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-06-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- C2 domain containing protein kinases
- AGC family kinases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprotein kinase D1
-
Synonyms gene
-
Synonyms gene name
- protein kinase C, mu
-
Synonyms
-
Locus
-
Discovery year1994-05-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Pleckstrin homology domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameproline rich transmembrane protein 2
-
Synonyms gene
-
Synonyms gene name
- infantile convulsions and paroxysmal choreoathetosis
- dystonia 10
- proline-rich transmembrane protein 2
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2005-11-25
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- interferon induced transmembrane protein domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameprotein kinase, DNA-activated, catalytic subunit
-
Synonyms gene
-
Synonyms gene name
- protein kinase, DNA-activated, catalytic polypeptide
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1993-11-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Armadillo like helical domain containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data