Downregulator of Transcription 1 (DR1)

• Catalog number
  MBS614582
• Price
  Please ask
• Size
  50ug

• Alternative name1
  Anti-Downregulator of Transcription 1 (DR1)
• Alternative name2
  Downregulator of Transcription 1 (DR1)
• Alternative name3
  Downregulator of Transcription 1 (DR1)
• Alternative name4
  Downregulator of Transcription 1
• Alternative name5
  Anti -Downregulator of Transcription 1 (DR1)
• Other names
  N/A
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  IgY
• Clone
  Polyclonal antibody
• Host organism
  Host: Chicken; Source: Human
• Species reactivity
  Human, Mouse
• Specificity and cross reactivity
  Recognizes human Downregulator of Transcription 1. Species Crossreactivity: Mouse.
• Purification method
  Affinity Purified by immunoaffinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested for
  ELISA (EL/EIA), Western Blot (WB)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  Downregulator   Transcription   DR1  
• Gene symbol
  DR1, CHRFAM7A
• Short name
  Downregulator of Transcription 1 (DR1)
• Alternative name
  Downregulator on Transcription 1 (DR1)

Gene info

• Identity
  HGNC:3017
• Gene
  DR1
• Long gene name
  down-regulator of transcription 1
• Synonyms gene name
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Synonyms
  • NC2-BETA
  • NC2B
  • NCB2
• Synonyms name
  • negative cofactor 2
  • negative cofactor 2 beta
• GenBank acession
  • M97388
• Locus
  1p22.1
• Discovery year
  1996-07-11
• Entrez gene record
  1810
• Pubmed identfication
  • 1339312
  • 9040789
• RefSeq identity
  • NM_001938
• Classification
  • ATAC complex
• VEGA ID
  OTTHUMG00000010862

Gene info

• Identity
  HGNC:15781
• Gene
  CHRFAM7A
• Long gene name
  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
• Synonyms gene name
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
• Synonyms
  • D-10
  • CHRNA7-DR1
• GenBank acession
  • AF029838
• Locus
  15q13.2
• Discovery year
  2001-06-29
• Entrez gene record
  89832
• Pubmed identfication
  • 11829490
• RefSeq identity
  • NM_148911
• VEGA ID
  OTTHUMG00000175645

MeSH Data

• Name
  Gene Knockdown Techniques
• Concept
  Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
• Tree numbers
  • E05.393.335.500
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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