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Also known as
p53
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Other names
P53; Cellular tumor antigen p53; cellular tumor antigen p53; antigen NY-CO-13; OTTHUMP00000221333; OTTHUMP00000221334; OTTHUMP00000221336; OTTHUMP00000221337; OTTHUMP00000221340; phosphoprotein p53; p53 tumor suppressor; transformation-related protein 53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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Gene name synonims
TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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Other gene names
TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG
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Clone
8A24
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Detects endogenous levels of p53 only when phosphorylated at Ser15. The antibody does not cross-react with p53 phosphorylated at other sites. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
As reported
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Form Appearance
Supplied in PBS (pH 7.2), 0.1% sodium azide, 2mg/ml BSA.
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Concentration
N/A
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Storage and shipping
Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do Not Freeze. Aliquots are stable for at least 12 months. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer. AlexaFluor conjugates are sensitive to light.
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Tested applications
Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the p53, phosphorylated (Ser15) (Tumor Suppressor Protein, Oncogene Protein) ( ) has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.
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Conjugation
Alexa Fluor
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Description
Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
