p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)

• Catalog number
  MBS628846
• Price
  Please ask
• Size
  100ul

• Alternative name1
  Anti-p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Alternative name2
  p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Alternative name3
  p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Alternative name4
  p53 Binding Protein 1
• Alternative name5
  Anti -p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Other names
  P53; N/A
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  IgG
• Clone
  Polyclonal antibody
• Host organism
  Host: Rabbit; Source: Human
• Species reactivity
  Human, Monkey
• Specificity and cross reactivity
  Recognizes endogenous levels of 53BP1 only when phosphorylated at serine 1778. Species crossreactivity: Monkey.
• Purification method
  Affinity Purified by Protein A and peptide affinity chromatography.
• Form Appearance
  Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, < 0.02% sodium azide, 50% glycerol.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested for
  Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  p53   Binding   Protein   phosphorylated   Ser1778   53BP1   53-BP1   FLJ41424   MGC138366   p202   p53BP1   Tumor   Protein   Binding   Protein   Tumor   Protein   p53   Binding   Protein   TP53BP1   Tumor   Suppressor   p53   Binding   Protein  
• Gene symbol
  TP53BP1, IGLVIV-53, IGHV3-53, IGHVII-53-1, SIGMAR1, IGFBP3, RNU6-53P, SNORD8, REXO1, EIF4EBP1
• Short name
  p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Alternative name
  p53 Binding Protein 1, phosphorylated (Ser1778) (53BP1, 53-BP1, FLJ41424, MGC138366, p202, p53BP1, Tumor Protein 53 Binding Protein 1, Tumor Protein p53 Binding Protein 1, TP53BP1, Tumor Suppressor p53 Binding Protein 1)
• Tissue
  tumor

Gene info

• Identity
  HGNC:11999
• Gene
  TP53BP1
• Long gene name
  tumor protein p53 binding protein 1
• Synonyms gene name
  • tumor protein p53-binding protein, 1
• Synonyms
  • 53BP1
  • p202
  • TDRD30
• GenBank acession
  • U09477
• Locus
  15q15.3
• Discovery year
  2000-06-24
• Entrez gene record
  7158
• Pubmed identfication
  • 8016121
  • 9748285
• Classification
  • Tudor domain containing
• VEGA ID
  OTTHUMG00000059757

Gene info

• Identity
  HGNC:5941
• Gene
  IGLVIV-53
• Long gene name
  immunoglobulin lambda variable (IV)-53 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (IV)-53
  • immunoglobulin lambda variable (IV)-53 pseudogene
• Synonyms
  • IGLV(IV)-53
• GenBank acession
  • D86996
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28762
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151585

Gene info

• Identity
  HGNC:5610
• Gene
  IGHV3-53
• Long gene name
  immunoglobulin heavy variable 3-53
• GenBank acession
  • M99679
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28420
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151966

Gene info

• Identity
  HGNC:5685
• Gene
  IGHVII-53-1
• Long gene name
  immunoglobulin heavy variable (II)-53-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-53-1
  • immunoglobulin heavy variable (II)-53-1 pseudogene
• Synonyms
  • IGHV(II)-53-1
• GenBank acession
  • AB019438
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28362
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151954

Gene info

• Identity
  HGNC:8157
• Gene
  SIGMAR1
• Long gene name
  sigma non-opioid intracellular receptor 1
• Synonyms gene
  • OPRS1
• Synonyms gene name
  • opioid receptor, sigma 1
• Synonyms
  • SR-BP1
• GenBank acession
  • BC004899
• Locus
  9p13.3
• Discovery year
  1993-03-11
• Entrez gene record
  10280
• Pubmed identfication
  • 8954936
  • 9453537
• RefSeq identity
  • NM_005866
• VEGA ID
  OTTHUMG00000019829

Gene info

• Identity
  HGNC:5472
• Gene
  IGFBP3
• Long gene name
  insulin like growth factor binding protein 3
• Synonyms gene name
  • insulin-like growth factor binding protein 3
• Synonyms
  • IBP3
  • BP-53
• Synonyms name
  • growth hormone-dependent binding protein
  • acid stable subunit of the 140 K IGF complex
  • binding protein 53
  • binding protein 29
  • IGF-binding protein 3
• Locus
  7p12.3
• Discovery year
  1991-07-09
• Entrez gene record
  3486
• Pubmed identfication
  • 1695633
• RefSeq identity
  • NM_001013398
• Classification
  • Insulin like growth factor binding proteins
• VEGA ID
  OTTHUMG00000023769
• Locus Specific Databases
  • LRG_68

Gene info

• Identity
  HGNC:42543
• Gene
  RNU6-53P
• Long gene name
  RNA, U6 small nuclear 53, pseudogene
• Synonyms gene
  • RNU6-53
• Synonyms gene name
  • RNA, U6 small nuclear 53
• Locus
  13q12.3
• Discovery year
  2011-08-08
• Entrez gene record
  100873762
• RefSeq identity
  • NR_046928

Gene info

• Identity
  HGNC:20159
• Gene
  SNORD8
• Long gene name
  small nucleolar RNA, C/D box 8
• Synonyms gene
  • RNU6C
• Synonyms gene name
  • RNA, U6C small nucleolar
• Synonyms
  • mgU6-53
• GenBank acession
  • AJ243222
• Locus
  14q11.2
• Discovery year
  2003-01-13
• Entrez gene record
  319103
• Pubmed identfication
  • 10490628
• RefSeq identity
  • NR_002916
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:24616
• Gene
  REXO1
• Long gene name
  RNA exonuclease 1 homolog
• Synonyms gene
  • TCEB3BP1
• Synonyms gene name
  • transcription elongation factor B polypeptide 3 binding protein 1
  • REX1, RNA exonuclease 1 homolog (S. cerevisiae)
• Synonyms
  • EloA-BP1
  • KIAA1138
• Synonyms name
  • elongin A binding protein 1
• GenBank acession
  • AB032964
• Locus
  19p13.3
• Discovery year
  2004-01-16
• Entrez gene record
  57455
• Pubmed identfication
  • 10574461
• RefSeq identity
  • NM_020695
• Classification
  • MicroRNA protein coding host genes
  • Exonucleases
• VEGA ID
  OTTHUMG00000179991

Gene info

• Identity
  HGNC:3288
• Gene
  EIF4EBP1
• Long gene name
  eukaryotic translation initiation factor 4E binding protein 1
• Synonyms
  • PHAS-I
  • 4E-BP1
• Synonyms name
  • phosphorylated heat- and acid-stable protein regulated by insulin 1
• Locus
  8p11.23
• Discovery year
  1996-10-26
• Entrez gene record
  1978
• Pubmed identfication
  • 7935836
• RefSeq identity
  • NM_004095
• VEGA ID
  OTTHUMG00000164012

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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