Mitomycin C

  • Catalog number
    2713-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; Ametycine
  • Description
    Mitomycin C is an antitumor antibiotic isolated from Streptomyces sp. Mitomycin is activated by reduction in vivo generating oxygen radicals which produce crosslinks in DNA by alkylaion. This mechanism ultimately inhibits DNA synthesis which has a bacteriostatic effect. Mitomycin C has strong antitumor activity, especially against Ehrlich ascites tumor cells, and strong bactericidal action against gram-positive and gram-negative bacteria.
  • CAS Number
    50-07-7
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₈N₄O₅
  • Molecular Weight
    334.33
  • Cell Permeable
    No
  • Purity
    Potency: ≥970 µg/mg
  • Solubilities
    DMSO (~15 mg/ml) or H₂O (~0.5 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    An antitumor antibiotic
  • Storage Condition
    +4°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00078109
  • PubChem CID
    5746
  • SMILES
    CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
  • InChi
    InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
  • InChi Key
    NWIBSHFKIJFRCO-WUDYKRTCSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Mitomycin C
  • Alternative name
    Mitomycin C
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