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Alternative_name
3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one, CLZN
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Description
Cell-permeable. Coelenterazine is the luminescent substrate for Renilla luciferase and apoaequorin. When coelenterazine combines with luciferase, oxygen, and calcium ions, it produces oxy-coelenterazine and light. This allows coelenterazine to be used for bioluminescent calcium detection and the monitoring of reporter genes in BRET (Bioluminescence Resonance Energy Transfer), ELISA and HTS methods as well as chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues.
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CAS Number
55779-48-1
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₆H₂₁N₃O₃
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Molecular Weight
423.46
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Cell Permeable
Yes
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Purity
≥95% by TLC
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Solubilities
EtOH or MeOH
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Handling
Protect from air and moisture
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Tag Line
A luminescent substrate
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Storage Condition
-20 ̊C
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Shipping Condition
gel pack
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Shelf Life
24 months
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MDL Number
MFCD00467176
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PubChem CID
2830
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SMILES
C1=CC=C(C=C1)CC2=C3N=C(C(=O)N3C=C(N2)C4=CC=C(C=C4)O)CC5=CC=C(C=C5)O
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InChi
InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
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InChi Key
YHIPILPTUVMWQT-UHFFFAOYSA-N
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MSDS Available
Yes