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Also known as
Leucine-rich repeat-containing G-protein coupled receptor 5
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Other names
leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1; Leucine-rich repeat-containing G-protein coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; orphan G protein-coupled receptor HG38; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat containing G protein-coupled receptor 5; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
LGR5; LGR5; FEX; HG38; GPR49; GPR67; GRP49; GPR49; GPR67
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Gene name synonims
LGR5; LGR5; FEX; HG38; GPR49; GPR67; GRP49; GPR49; GPR67
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Other gene names
LGR5; LGR5; FEX; HG38; GPR49; GPR67; GRP49; GPR49; GPR67
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1 for MAb 1209-E3 IgG2a for MAb 1208-C2
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Clone
1208-C2, 1209-E3
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Host organism
N/A
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Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
MAb 1208-C2: Peptide CENAYKISNQWNKGDNSSM. MAb 1209-E3: Peptide YDLPPSSVPSPAYPVTE; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Chromatography on protein G Sepharose
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Form Appearance
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius.
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Tested applications
Peptide ELISA (EIA)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
