OVA conjugated Neurofilament, Light Polypeptide (NEFL)

• Catalog number
  RPU50898-1mg
• Price
  Please ask
• Size
  1mg

• Estimated Turnaround Time
  6-11 business days
• Gene Name
  NA
• Alternative Names
  CMT1F; CMT2E; NF-L; NF68; NFL; 68 kDa neurofilament protein; Neurofilament triplet L protein
• Source
  Chemical synthesis
• Purity
  > 90%
• Application
  Immunogen; SDS-PAGE; WB
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  1 year
• Restriction
  For research use only. Not for diagnostic procedures.
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

• Gene target
  OVA   conjugated   Neurofilament   Light   Polypeptide   NEFL  
• Gene symbol
  NEFL
• Short name
  OVA conjugated Neurofilament, Light Polypeptide (NEFL)
• Technique
  light, antibody Conjugates
• Species
  Homo sapiens (Human)
• Alternative name
  OVA coupled Neurofilament, Light multipeptide (neurofilament, light polypeptide)
• Alternative to gene target
  neurofilament, light polypeptide, CMT1F and CMT2E and NF-L and NF68 and NFL and PPP1R110, NEFL and IDBG-777808 and ENSG00000277586 and 4747, protein binding, Cytoplasm, Nefl and IDBG-176493 and ENSMUSG00000022055 and 18039, NEFL and IDBG-635366 and ENSBTAG00000021949 and 281348

Gene info

• Identity
  HGNC:7739
• Gene
  NEFL
• Long gene name
  neurofilament light chain
• Synonyms gene name
  • neurofilament, light polypeptide 68kDa
  • neurofilament, light polypeptide
  • neurofilament light
• Synonyms
  • NFL
  • CMT1F
  • CMT2E
  • NF68
  • PPP1R110
• Synonyms name
  • protein phosphatase 1, regulatory subunit 110
• Locus
  8p21.2
• Discovery year
  2001-06-22
• Entrez gene record
  4747
• Pubmed identfication
  • 17620486
  • 3145240
• RefSeq identity
  • NM_006158
• Classification
  • Intermediate filaments Type IV
  • Protein phosphatase 1 regulatory subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000134284
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_259

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