BFSP2/Phakinin Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11015R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  BFSP2/Phakinin Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-BFSP2/Phakinin PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BFSP2/Phakinin
• Specificity
  This is a highly specific antibody against BFSP2/Phakinin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BFSP2/Phakinin
• Gene ID Number
  3921
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  49 kDa cytoskeletal protein; Beaded filament protein CP49; Beaded filament structural protein 2; Beaded filament structural protein 2, phakinin; Bfps2, Cytoskeletal protein, 49 kD; BFSP2; BFSP2_HUMAN; CP47; CP49; Lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49;Lens intermediate filament-like light; LL-L; Phakinin; PHAKOSIN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-BFSP2/Phakinin has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  BFSP2/Phakinin  
• Gene symbol
  BFSP2-AS1, BFSP2
• Short name
  Anti-BFSP2/Phakinin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  BFSP2/Phakinin Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:28425
• Gene
  BFSP2-AS1
• Long gene name
  BFSP2 antisense RNA 1
• Synonyms
  • MGC2848
• Locus
  3q22.1
• Discovery year
  2013-09-02
• Entrez gene record
  85003
• Pubmed identfication
  • 12477932
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000159721

Gene info

• Identity
  HGNC:1041
• Gene
  BFSP2
• Long gene name
  beaded filament structural protein 2
• Synonyms gene name
  • beaded filament structural protein 2, phakinin
• Synonyms
  • CP47
  • CP49
  • LIFL-L
  • phakinin
• GenBank acession
  • U48224
• Locus
  3q22.1
• Discovery year
  1999-04-14
• Entrez gene record
  8419
• Classification
  • Beaded filament structural proteins
• VEGA ID
  OTTHUMG00000159719
• Locus Specific Databases
  • Human Intermediate Filament Mutation Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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