LAMP-1 Antibody (Center)
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Catalog number5077-100
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PricePlease ask
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Size100 µg
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Antibody TargetLAMP-1
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Target Alternative NameLAMP-1, Lysosome associated membrane protein 1
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceLAMP-1 antibody was raised against a 15 amino acid peptide from near the center of human LAMP-1.
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AccessionP11279
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Gene Id3916
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AppearanceColorless liquid
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FormLiquid
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Concentration1 mg/ml
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Formulation100 µg (1 mg/ml) in 1X PBS containing 0.02% sodium azide.
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PurificationAffinity chromatography purified via peptide column.
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ApplicationWestern blot, Immunofluorescence, ELISA
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Positive ControlWestern Blot: EL4 cell lysate Immunofluorescence: Human colon tissue
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Application And UsagesWestern Blot: 1 - 2 μg/ml, Immunofluorescence: 20 μg/ml, ELISA. However, the optimal conditions should be determined individually.
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DescriptionAutophagy, the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome. LAMP-1 shares much homology to LAMP-2 and is thoμght to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression. However, the loss of both proteins resulted in embryonic lethality, sμggesting that each protein possesses some unique and necessary functions.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedVerified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedVerified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolLAMP1, LAMP3, LSAMP, LAMP5, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
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Short nameLAMP-1 Antibody (Center)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG1
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Alternative nameLAMP-1 (antibody to-) (central)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein 1
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Synonyms gene name
- lysosomal-associated membrane protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-07-15
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Entrez gene record
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Classification
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein 3
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Synonyms gene name
- lysosomal-associated membrane protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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Classification
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelimbic system associated membrane protein
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Synonyms gene name
- limbic system-associated membrane protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I-set domain containing
- IgLON cell adhesion molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein family member 5
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Synonyms gene
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Synonyms gene name
- chromosome 20 open reading frame 103
- lysosomal-associated membrane protein family, member 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Lysosome associated membrane proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data