Caspase-6 (Active) Antibody
-
Catalog number
3156-100
-
Price
Please ask
-
Size
100 µg
-
-
Antibody Target
Caspase-6 (Active)
-
Target Alternative Name
CASP6, CASP-6 , MCH2
-
Antibody Type
Polyclonal
-
Species Reactivities
Human, mouse, rat
-
Immunogen Sequence
Synthetic peptide surrounding amino acids mapping to the C-terminus of the large fragment of human caspase-6
-
Accession
AAH00305
-
Gene Id
839
-
Appearance
Colorless liquid
-
Form
Liquid
-
Concentration
0.5 mg/ml
-
Formulation
100 µg (0.5 mg/ml) affinity purified rabbit anti-active caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
-
Purification
Affinity purified
-
Application
Western blot
-
Application And Usages
Western blotting (0.5-4 µg/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases.
-
Description
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.
-
Storage Condition
-20 °C
-
Shipping Condition
gel pack
-
Shelf Life
12 months
-
Usage
For Research Use Only! Not to be used in humans.
-
Handling
The antibody solution should be gently mixed before use.
-
Western Blot Verified
Verified
-
Immunocytochemistry Verified
Not Verified
-
Immunofluorescence Verified
Not Verified
-
Immunoprecipitation Verified
Not Verified
-
ELISA Verified
Not Verified
-
ChIP Verified
Not Verified
-
Flow Cytometry Verified
Not Verified
-
-
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
-
French translation
anticorps
-
Gene target
-
Short name
Caspase-6 (Active) Antibody
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Rabbit IgG
-
Alternative name
caspase-6 (functionnal) (antibody to-)
-
Alternative technique
antibodies
-
MeSH Data
-
Name
-
Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
-
Tree numbers
Product images
Similar products