ARID1B Antibody

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• Catalog number
  bs-12520R
• Price:

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• Size
  0.1ml

# #

• Long name
  ARID1B Primary Polyclonal Antibody
• Also known as
  ARID1B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ARID1B
• Specificity
  This is a highly specific antibody against ARID1B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1550-1600/2236
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARID1B
• Gene ID number
  57492
• Swiss Prot
  Q8NFD5
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  OSA2; 6A3-5; DAN15; MRD12; P250R; BRIGHT; BAF250B; ELD/OSA1; AT-rich interactive domain-containing protein 1B; ARID domain-containing protein 1B; BRG1-associated factor 250b; BRG1-binding protein hELD/OSA1; Osa homolog 2; hOsa2; ARID1B; KIAA1235
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

#

• Gene target
  ARID1B  
• Gene symbol
  ARID1B
• Short name
  Anti-ARID1B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ARID1B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18040
• Gene
  ARID1B
• Long gene name
  AT-rich interaction domain 1B
• Synonyms gene name
  • AT rich interactive domain 1B (SWI1-like)
• Synonyms
  • KIAA1235
  • ELD/OSA1
  • p250R
  • BAF250b
  • DAN15
  • 6A3-5
  • SMARCF2
• GenBank acession
  • AF521671
• Locus
  6q25.3
• Discovery year
  2004-01-28
• Entrez gene record
  57492
• RefSeq identity
  • NM_020732
• Classification
  • Armadillo like helical domain containing
  • AT-rich interaction domain containing
  • BAF complex
• VEGA ID
  OTTHUMG00000015890

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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