anti- CYP46A1 antibody

• Catalog number
  FNab02167
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
• Immunogen
  cytochrome P450, family 46, subfamily A, polypeptide 1
• Synonyms
  CYP46
• Calculated MW
  57 kDa
• Uniprot ID
  Q9Y6A2
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human gliomas using FNab02167(CYP46A1 antibody) at dilution of 1:50
• Image4
  human brain tissue were subjected to SDS PAGE followed by western blot with FNab02167(CYP46A1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CYP46A1  
• Gene symbol
  CYP46A1
• Short name
  anti- CYP46A1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- CYP46A1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2641
• Gene
  CYP46A1
• Long gene name
  cytochrome P450 family 46 subfamily A member 1
• Synonyms gene
  • CYP46
• Synonyms gene name
  • cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
  • cytochrome P450, family 46, subfamily A, polypeptide 1
• GenBank acession
  • AF094480
• Locus
  14q32.2
• Discovery year
  1999-08-20
• Entrez gene record
  10858
• Pubmed identfication
  • 10377398
• Classification
  • Cytochrome P450 family 46
• VEGA ID
  OTTHUMG00000171510

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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