IC87114

• Catalog number
  1661-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  2-[6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
• Description
  Cell-permeable. A potent, ATP-competitive and selective inhibitor of PI 3-K isoform p110δ (IC₅₀ = 60 nM). Inhibits p110α and p110β only at higher concentrations (>1 µM). IC87114 does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100 µM.
• CAS Number
  371242-69-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₁₉N₇O
• Molecular Weight
  397.43
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A PI3 Kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD09970845
• PubChem CID
  9908783
• PubChem CID Link
• SMILES
  CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C4N=CN=C5N
• InChi
  InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22 (29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3, (H2,23,24,25)
• InChi Key
  GNWHRHGTIBRNSM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  IC87114  
• Short name
  IC87114
• Alternative name
  IC87114

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