Anti-MMP-8 Antibody

• Catalog number
  3528R-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  MMP-8
• Target Alternative Name
  MMP8 ,120355 , P22894 , CLG1 , HNC, PMNL-CL , EC 3.4.24.34 , MMP-8 , Matrix metalloproteinase
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 448 of rat MMP-8
• Accession
  O88766
• Gene Id
  63849
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  In phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (1-4 µg/ml). Other applications have not been tested. Blocking peptide (Cat.# 3528RBP-50) is available separately. The antibody recognizes latent (85 kDa) and active forms (25-65 kDa) of MMP8 from human, mouse, and rat origins.
• Description
  The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. Unlike other members of the MMP family, MMP-8 is expressed exclusively in inflammatory conditions. MMP-8 is also the predominant collagenase expressed in ulcers and healing wounds.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MMP-8  
• Gene symbol
  MMP8, MMP24, MMP14, MMP28, MMP17, SNORD114-8, RNU6-8, SNORD113-8, SNORD116-8, IGKV2OR2-8
• Short name
  Anti-MMP-8 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toMMP-8 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7175
• Gene
  MMP8
• Long gene name
  matrix metallopeptidase 8
• Synonyms gene
  • CLG1
• Synonyms gene name
  • matrix metalloproteinase 8 (neutrophil collagenase)
• GenBank acession
  • J05556
• Locus
  11q22.2
• Discovery year
  1991-09-11
• Entrez gene record
  4317
• RefSeq identity
  • NM_002424
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000167587

Gene info

• Identity
  HGNC:7172
• Gene
  MMP24
• Long gene name
  matrix metallopeptidase 24
• Synonyms gene name
  • matrix metalloproteinase 24 (membrane-inserted)
  • matrix metallopeptidase 24 (membrane-inserted)
• Synonyms
  • MT5-MMP
• Synonyms name
  • membrane-type 5 matrix metalloproteinase
• GenBank acession
  • AF131284
• Locus
  20q11.22
• Discovery year
  1999-08-06
• Entrez gene record
  10893
• Pubmed identfication
  • 10363975
• RefSeq identity
  • NM_006690
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000032330

Gene info

• Identity
  HGNC:7160
• Gene
  MMP14
• Long gene name
  matrix metallopeptidase 14
• Synonyms gene name
  • matrix metalloproteinase 14 (membrane-inserted)
  • matrix metallopeptidase 14 (membrane-inserted)
• Synonyms
  • MT1-MMP
• Synonyms name
  • membrane type 1 metalloprotease
  • membrane type 1-matrix metalloproteinase
• Locus
  14q11.2
• Discovery year
  1994-11-20
• Entrez gene record
  4323
• Pubmed identfication
  • 8015608
• RefSeq identity
  • NM_004995
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000028704

Gene info

• Identity
  HGNC:14366
• Gene
  MMP28
• Long gene name
  matrix metallopeptidase 28
• Synonyms gene name
  • matrix metalloproteinase 28
• Synonyms
  • MMP-25
  • MM28
  • EPILYSIN
  • MMP-28
• GenBank acession
  • AF315683
• Locus
  17q12
• Discovery year
  2001-01-09
• Entrez gene record
  79148
• Pubmed identfication
  • 11121398
  • 11255011
• RefSeq identity
  • NM_024302
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000188387

Gene info

• Identity
  HGNC:7163
• Gene
  MMP17
• Long gene name
  matrix metallopeptidase 17
• Synonyms gene name
  • matrix metalloproteinase 17 (membrane-inserted)
  • matrix metallopeptidase 17 (membrane-inserted)
• Synonyms
  • MT4-MMP
• GenBank acession
  • X89576
• Locus
  12q24.33
• Discovery year
  1996-11-13
• Entrez gene record
  4326
• Pubmed identfication
  • 9878265
• RefSeq identity
  • NM_016155
• Classification
  • M10 matrix metallopeptidases
• VEGA ID
  OTTHUMG00000168050

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:32987
• Gene
  SNORD113-8
• Long gene name
  small nucleolar RNA, C/D box 113-8
• Synonyms
  • 14q(I-8)
• Locus
  14q32.31
• Discovery year
  2006-09-20
• Entrez gene record
  767568
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003236.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33074
• Gene
  SNORD116-8
• Long gene name
  small nucleolar RNA, C/D box 116-8
• Synonyms
  • HBII-85-8
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033420
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003323
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5811
• Gene
  IGKV2OR2-8
• Long gene name
  immunoglobulin kappa variable 2/OR2-8 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-8
  • immunoglobulin kappa variable 2/OR2-8 pseudogene
• Synonyms
  • IGKV2/OR2-8
• GenBank acession
  • X51880
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  100996600
• RefSeq identity
  • NG_011662
• Classification
  • Immunoglobulin kappa (IGK) orphons

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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