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Also known as
CD15
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Other names
alpha-(1,3)-fucosyltransferase 4; Alpha-(1,3)-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 4; Lewis X; fucT-IV; fucosyltransferase IV; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; galactoside 3-L-fucosyltransferase; stage-specific embryonic antigen 1; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
FUT4
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Gene name synonims
N/A
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Other gene names
FUT4; FUT4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; ELFT; FCT3A; Fuc-TIV; FucT-IV
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Clonality
Monoclonal
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Immunoglobulin isotype
IgM, kappa
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Clone
SPM119
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
N/A
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Concentration
N/A
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Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applications
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistology (IH)
