anti- CDC42 antibody

• Catalog number
  FNab01530
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
• Immunogen
  cell division cycle 42 (GTP binding protein, 25kDa)
• Synonyms
  CDC42Hs;G25K;TKS
• Calculated MW
  21 kDa
• Uniprot ID
  P60953
• Specificity
  Human, Mouse
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab01530(CDC42 antibody) at dilution of 1:50
• Image4
  mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01530(CDC42 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CDC42  
• Gene symbol
  CDC42-AS1, CDC42-IT1, CDC42
• Short name
  anti- CDC42 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- cellular division cycle 42 (GTP binding protein, 25kDa) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  cell division cycle 42 (GTP binding protein, 25kDa), CDC42Hs and G25K, CDC42 and IDBG-93614 and ENSG00000070831 and 998, identical protein binding, Cell surfaces, Cdc42 and IDBG-198471 and ENSMUSG00000006699 and 12540, BT.56113 and IDBG-645532 and ENSBTAG00000001700 and 532712

Gene info

• Identity
  HGNC:54314
• Gene
  CDC42-AS1
• Long gene name
  CDC42 antisense RNA 1
• Locus
  1p36.12
• Discovery year
  2019-05-03
• Entrez gene record
  112268223
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:41317
• Gene
  CDC42-IT1
• Long gene name
  CDC42 intronic transcript 1
• Synonyms gene name
  • CDC42 intronic transcript 1 (non-protein coding)
• Locus
  1p36.12
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000002890

Gene info

• Identity
  HGNC:1736
• Gene
  CDC42
• Long gene name
  cell division cycle 42
• Synonyms gene name
  • cell division cycle 42 (GTP-binding protein, 25kD)
  • cell division cycle 42 (GTP binding protein, 25kDa)
• Synonyms
  • G25K
  • CDC42Hs
• Synonyms name
  • GTP binding protein, 25kDa
• GenBank acession
  • BC018266
• Locus
  1p36.12
• Discovery year
  1991-06-06
• Entrez gene record
  998
• Pubmed identfication
  • 2124704
  • 2122236
• RefSeq identity
  • NM_001791
• Classification
  • Rho family GTPases
• VEGA ID
  OTTHUMG00000002753
• Locus Specific Databases
  • LRG_1326

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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