PF-4/CXCL4, murine recombinant

• Catalog number
  7187-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Platelet Factor-4, CXCL4, Oncostatin A, Ironplact
• Alternative_names
  Platelet Factor-4, CXCL4, Oncostatin A, Ironplact
• Description
  Involved in inhibition of angiogenesis
• Recombinant
  Yes
• Source
  E. Coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
• Molecular Weight
  10.3 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized with no additives
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.
• Amino acid sequence
  VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PF-4/CXCL4   murine  
• Gene symbol
  PF4, MIR1302-4, PIRC18, PIRC16, SNORD114-4, IGKV2OR2-4, MIR941-4, PIRC19
• Short name
  PF-4/CXCL4, murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  PF-4/CXCL4, murine Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8861
• Gene
  PF4
• Long gene name
  platelet factor 4
• Synonyms
  • SCYB4
  • CXCL4
• Synonyms name
  • chemokine (C-X-C motif) ligand 4
• GenBank acession
  • M25897
• Locus
  4q13.3
• Discovery year
  2001-06-22
• Entrez gene record
  5196
• Pubmed identfication
  • 3622011
• VEGA ID
  OTTHUMG00000130009
• Locus Specific Databases
  • LRG_636

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:37523
• Gene
  PIRC19
• Long gene name
  piwi-interacting RNA cluster 19
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313926
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Urine Specimen Collection
• Concept
  Scope note: Methods or procedures used to obtain samples of URINE.
• Tree numbers
  • E01.370.225.998.762
  • E05.200.998.762
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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