Bromodomain Testis-specific Protein (BrdT), human recombinant
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Catalog number
7641-1000
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Price
Please ask
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Size
1 mg
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Synonyms
Recombinant Human Bromodomain Testis-specific Protein (BrdT)
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Alternative_names
BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
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Description
A protein driving meiotic and post-meiotic gene expression program
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥98%
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Assay
SDS-PAGE
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Molecular Weight
13.9 kDa (117aa, 22-138 +NT-His Tag)
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Storage Temp
-80°C
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Shipping
Dry ice
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Shelf Life
12 months
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Appearance
Liquid
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Physical form description
rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
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Background Information
BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVision’s recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Short name
Bromodomain Testis-specific Protein (BrdT), recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Bromodomain Testis-specific Protein (BrdT), H. sapiens Rec.
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Alternative technique
rec
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Tissue
testis
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MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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