Rat B7-H6 / B7H6 / NCR3LG1 Protein (His Tag) 200µg

• Catalog number
  PKSR030135-200µg
• Price
  Please ask
• Size
  200µg

• Synonym
  B7H6
• Activity
  NA
• Sequence
  Met1-Ser308
• Fusion tag
  C-His
• Accession
  XP_006223356.1
• ExpressedHost
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE.
• Endotoxin
  < 1.0 EU per μg protein as determined by the LAL method.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  35.1 kDa
• AP Mol Mass
  35.1 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  Natural cytotoxicity triggering receptor 3 ligand 1(B7-H6) is a glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H6 consists of a 238 amino acid (aa) extracellular domain (ECD) that contains one Ig-like V domain and one Ig-like C1 domain, a 21 aa transmembrane segment, and a 171 aa cytoplasmic domain that contains one ITIM, one SH2, and one SH3 motif. Both of the Ig-like domains carry N-linked glycosylation. The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells. It does not show binding to NKp44, NKp46, or NKG2D. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells, which is consistent with the detection of NKp30 binding sites on many tumors.
• Technical Data
• Conjugation
  histidine
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus

• Gene target
  B7-H6   B7H6   NCR3LG1   Protein   His   Tag   200µg  
• Gene symbol
  NCR3LG1, HHLA2, HMX1, RNY4P2, LRRC23, PCDHGB7, CD274, CD86, NME6, TLX1NB
• Short name
  B7-H6 / B7H6 / NCR3LG1 Protein (His Tag) 200µg
• Technique
  Tags
• Host
  Rat
• Label
  His
• Species
  Rat, Rats
• Alternative name
  Rat B7-H6 / B7H6 / NCR3LG1 Protein (histidine detection labelled) 200µg

Gene info

• Identity
  HGNC:42400
• Gene
  NCR3LG1
• Long gene name
  natural killer cell cytotoxicity receptor 3 ligand 1
• Synonyms
  • DKFZp686O24166
  • B7-H6
• Synonyms name
  • B7 homolog 6
• Locus
  11p15.1
• Discovery year
  2012-04-12
• Entrez gene record
  374383
• Pubmed identfication
  • 19528259
• RefSeq identity
  • NM_001202439
• Classification
  • Receptor ligands
  • C1-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000165913

Gene info

• Identity
  HGNC:4905
• Gene
  HHLA2
• Long gene name
  HERV-H LTR-associating 2
• Synonyms
  • B7H7
  • B7-H5
  • B7y
  • B7-H7
• GenBank acession
  • AF126162
• Locus
  3q13.13
• Discovery year
  1999-09-07
• Entrez gene record
  11148
• Pubmed identfication
  • 10444326
  • 23784006
  • 22488247
• RefSeq identity
  • NM_007072
• Classification
  • C1-set domain containing
  • V-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000159224

Gene info

• Identity
  HGNC:5017
• Gene
  HMX1
• Long gene name
  H6 family homeobox 1
• Synonyms gene name
  • homeo box (H6 family) 1
• Synonyms
  • H6
  • NKX5-3
• GenBank acession
  • M99587
• Locus
  4p16.1
• Discovery year
  1994-12-19
• Entrez gene record
  3166
• Pubmed identfication
  • 1360670
• RefSeq identity
  • NM_018942
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000160012

Gene info

• Identity
  HGNC:10246
• Gene
  RNY4P2
• Long gene name
  RNY4 pseudogene 2
• Synonyms gene name
  • RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
  • RNA, Ro-associated Y4 pseudogene 2
• Synonyms
  • hY4.B7
• GenBank acession
  • M77130
• Locus
  17q21.31
• Discovery year
  1993-08-25
• Entrez gene record
  6088
• RefSeq identity
  • NG_005037

Gene info

• Identity
  HGNC:19138
• Gene
  LRRC23
• Long gene name
  leucine rich repeat containing 23
• Synonyms
  • B7
  • LRPB7
• GenBank acession
  • BC014450
• Locus
  12p13.31
• Discovery year
  2006-01-24
• Entrez gene record
  10233
• Pubmed identfication
  • 11830501
  • 11826754
• RefSeq identity
  • NM_006992
• VEGA ID
  OTTHUMG00000156668

Gene info

• Identity
  HGNC:8714
• Gene
  PCDHGB7
• Long gene name
  protocadherin gamma subfamily B, 7
• Synonyms
  • ME6
  • PCDH-GAMMA-B7
• Synonyms name
  • cadherin ME6
• GenBank acession
  • AF152523
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56099
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018927
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000164054

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:1705
• Gene
  CD86
• Long gene name
  CD86 molecule
• Synonyms gene
  • CD28LG2
• Synonyms gene name
  • CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
• Synonyms
  • B7.2
  • B7-2
• Synonyms name
  • B-lymphocyte antigen B7-2
• Locus
  3q13.33
• Discovery year
  1994-12-07
• Entrez gene record
  942
• Pubmed identfication
  • 7513726
• RefSeq identity
  • NM_006889
• Classification
  • B7 family
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000159482

Gene info

• Identity
  HGNC:20567
• Gene
  NME6
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 6
• Synonyms gene name
  • non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • NM23-H6
  • IPIA-ALPHA
• GenBank acession
  • AF051941
• Locus
  3p21.31
• Discovery year
  2003-02-25
• Entrez gene record
  10201
• Pubmed identfication
  • 10453732
  • 19852809
• RefSeq identity
  • NM_005793
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000133531

Gene info

• Identity
  HGNC:37183
• Gene
  TLX1NB
• Long gene name
  TLX1 neighbor
• Synonyms
  • TD1
  • TDI
  • APT-B7
• Synonyms name
  • TLX1 divergent
• GenBank acession
  • BC019674
• Locus
  10q24.31
• Discovery year
  2009-08-14
• Entrez gene record
  100038246
• Pubmed identfication
  • 17303350
• RefSeq identity
  • NR_130722
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000018925

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