NOC-18

• Catalog number
  2492-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  Diethylenetriamine NONOate; DETA NONOate; (Z)-​1-​[N-​(2-​aminoethyl)-​N-​(2-​ammonioethyl)amino]diazen-​1-​ium-​1,​2-​diolate
• Description
  A useful nitric oxide (NO) donor. NOC-18 spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.
• CAS Number
  146724-94-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₄H₁₃N₅O₂
• Molecular Weight
  163.18
• Cell Permeable
  No
• Purity
  ≥98%
• Solubilities
  H2O or 0.1 M NaOH (10 mg/ml) or PBS
• Handling
  Protect from air and light
• Tag Line
  A nitric oxide (NO) donor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00278808
• PubChem CID
  1606
• PubChem CID Link
• SMILES
  C(CN(CCN)N(N=O)O)N
• InChi
  InChI=1S/C4H13N5O2/c5-1-3-8(4-2-6)9(11)7-10/h11H,1-6H2
• InChi Key
  HMRRJTFDJAVRMR-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  NOC-18  
• Gene symbol
  SNORD114-18, PIRC96, SNORD116-18, IGLV2-18, IGHV1-18, SNORD115-18, ERVW-18, NOCT, IGKV2D-18
• Short name
  NOC-18
• Alternative name
  NOC-18

Gene info

• Identity
  HGNC:33006
• Gene
  SNORD114-18
• Long gene name
  small nucleolar RNA, C/D box 114-18
• Synonyms
  • 14q(II-18)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767596
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003211.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:37600
• Gene
  PIRC96
• Long gene name
  piwi-interacting RNA cluster 96
• Locus
  18
• Discovery year
  2009-11-05
• Entrez gene record
  100313800
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33084
• Gene
  SNORD116-18
• Long gene name
  small nucleolar RNA, C/D box 116-18
• Synonyms
  • HBII-85-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033430
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003333
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5889
• Gene
  IGLV2-18
• Long gene name
  immunoglobulin lambda variable 2-18
• GenBank acession
  • Z73642
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28814
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151232

Gene info

• Identity
  HGNC:5549
• Gene
  IGHV1-18
• Long gene name
  immunoglobulin heavy variable 1-18
• GenBank acession
  • M99641
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28468
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152276

Gene info

• Identity
  HGNC:33037
• Gene
  SNORD115-18
• Long gene name
  small nucleolar RNA, C/D box 115-18
• Synonyms
  • HBII-52-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033456
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003310.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:49306
• Gene
  ERVW-18
• Long gene name
  endogenous retrovirus group W member 18
• Synonyms gene name
  • endogenous retrovirus group W, member 18
• GenBank acession
  • HG421056
• Locus
  6q24.2
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:14254
• Gene
  NOCT
• Long gene name
  nocturnin
• Synonyms gene
  • CCRN4L
• Synonyms gene name
  • CCR4-like (carbon catabolite repression 4, S.cerevisiae)
  • CCR4 carbon catabolite repression 4-like (S. cerevisiae)
• Synonyms
  • CCR4L
  • Ccr4c
  • NOC
• GenBank acession
  • AF183961
• Locus
  4q31.1
• Discovery year
  2000-12-14
• Entrez gene record
  25819
• Pubmed identfication
  • 10521507
  • 11394964
• RefSeq identity
  • NM_012118
• VEGA ID
  OTTHUMG00000161271

Gene info

• Identity
  HGNC:5794
• Gene
  IGKV2D-18
• Long gene name
  immunoglobulin kappa variable 2D-18 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-18
  • immunoglobulin kappa variable 2D-18 pseudogene
• GenBank acession
  • X63395
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28888
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151620

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