Langerin/CD207 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-2650R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Langerin/CD207 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Langerin/CD207
• Specificity
  This is a highly specific antibody against Langerin/CD207.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  213-223/328
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD207
• Gene ID Number
  50489
• Swiss Prot
  Q9UJ71
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Langerin/CD207 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Langerin/CD207  
• Gene symbol
  CD207
• Short name
  Anti-Langerin/CD207
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  CD207 molecule, langerin, CD207 and IDBG-55659 and ENSG00000116031 and 50489, carbohydrate binding, Plasma membranes, Cd207 and IDBG-161509 and ENSMUSG00000034783 and 246278, CD207 and IDBG-631820 and ENSBTAG00000004562 and 511000

Gene info

• Identity
  HGNC:17935
• Gene
  CD207
• Long gene name
  CD207 molecule
• Synonyms gene name
  • CD207 antigen, langerin
  • CD207 molecule, langerin
• Synonyms
  • Langerin
  • CLEC4K
• GenBank acession
  • AJ242859
• Locus
  2p13.3
• Discovery year
  2003-10-02
• Entrez gene record
  50489
• Pubmed identfication
  • 10661407
  • 9847074
• RefSeq identity
  • NM_015717
• Classification
  • Scavenger receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000153176

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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