Langerin/CD207 Antibody, ALEXA FLUOR 350
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Catalog number
bs-2650R-A350
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Price
Please ask
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Size
100ul
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Long name
Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known as
Anti-Langerin/CD207 PAb ALEXA FLUOR 350
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 350
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Langerin/CD207
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Specificity
This is a highly specific antibody against Langerin/CD207.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen range
213-223/328
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Subcellular location
Extracellular
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD207
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Gene ID Number
50489
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Swiss Prot
Q9UJ71
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
343nm/442nm
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Synonyms
CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 350
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French translation
anticorps
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Gene target
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Gene symbol
CD207
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Short name
Anti-Langerin/CD207
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 350
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Alternative name
Langerin/CD207 Polyclonal Antibody, ALEXA FLUOR 350
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Alternative technique
antibodies
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Alternative to gene target
CD207 molecule, langerin, CD207 and IDBG-55659 and ENSG00000116031 and 50489, carbohydrate binding, Plasma membranes, Cd207 and IDBG-161509 and ENSMUSG00000034783 and 246278, CD207 and IDBG-631820 and ENSBTAG00000004562 and 511000
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Gene info
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Identity
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Gene
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Long gene name
CD207 molecule
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Synonyms gene name
- CD207 antigen, langerin
- CD207 molecule, langerin
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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