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Also known as
P Selectin, Glycoprotein Ligand-1
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Other names
P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1; cutaneous lymphocyte-associated associated antigen; selectin P ligand; Selectin P ligand
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
SELPLG; SELPLG; CLA; CD162; PSGL1; PSGL-1; N/A
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Gene name synonims
SELPLG; SELPLG; CLA; CD162; PSGL1; PSGL-1; N/A
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Other gene names
SELPLG; SELPLG; CLA; CD162; PSGL1; PSGL-1; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
2Q745
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Host organism
Mouse (Mus musculus)
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Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Completely blocks recognition of PSGL-1 by either P-selectin or by L-selectin, but does not affect leukocyte recognition of E-selectin. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Purified immunoglobulin
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Form Appearance
Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
