Trichostatin A

  • Catalog number
    1606-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
  • Description
    Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.
  • CAS Number
    58880-19-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₂₂N₂O₃
  • Molecular Weight
    302.4
  • Cell Permeable
    Yes
  • Purity
    ≥99%
  • Solubilities
    DMSO (20 mg/ml) or EtOH (2 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A HDAC inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD03848392
  • PubChem CID
    444732
  • SMILES
    CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
  • InChi
    InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
  • InChi Key
    RTKIYFITIVXBLE-QEQCGCAPSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Trichostatin A
  • Alternative name
    Trichostatin A
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