Trichostatin A
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Catalog number1606-1
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PricePlease ask
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Size1 mg
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Alternative_nameTSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
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DescriptionPotent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.
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CAS Number58880-19-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₂₂N₂O₃
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Molecular Weight302.4
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Cell PermeableYes
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Purity≥99%
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SolubilitiesDMSO (20 mg/ml) or EtOH (2 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA HDAC inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD03848392
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PubChem CID444732
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SMILESCC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
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InChiInChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
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InChi KeyRTKIYFITIVXBLE-QEQCGCAPSA-N
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MSDS AvailableYes
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Gene target
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Short nameTrichostatin A
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Alternative nameTrichostatin A
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