CD70, Mouse IgG2a Fc Fusion Protein (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)[CD70 IgG2a Fc Fusion Protein]

• Catalog number
  MBS635192
• Price
  Please ask
• Size
  NA

• Products_type
  Protein
• Description
  Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  CD70   IgG2a   Protein   CD70   CD27   Ligand   CD27L   CD27-L   CD27LG   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   TNFSF7   [CD70   IgG2a   Protein]  
• Gene symbol
  CD70, CD27-AS1, CD27, CPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1, FABP1, COX7A2
• Short name
  CD70, Mouse IgG2a Fc Protein (CD70 Antigen, CD27 Ligand, CD27L, CD27-L, CD27LG, Tumor Necrosis Factor Ligand Superfamily Member 7, TNFSF7)[CD70 IgG2a Fc Protein]
• Technique
  antigen, Mouse, FC, antigenes, mouses
• Host
  mouse
• Isotype
  IgG2a
• Species
  Mouse, Mouses
• Alternative name
  CD70 molecule, Mouse IgG2a fragment c Fusion Protein (CD70 molecule protein, CD27 molecule Ligand, CD27L, CD27 molecule-L, CD27LG, Tumor Necrosis Factor Ligand supergroup Member 7, TNFSF7)[CD70 molecule IgG2a fragment c Fusion Protein]
• Alternative technique
  antigenes, murine
• Alternative to gene target
  CD27 molecule, S152 and S152. LPFS2 and T14 and TNFRSF7 and Tp55, CD27 and IDBG-14014 and ENSG00000139193 and 939, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, Extracellular, Cd27 and IDBG-189750 and ENSMUSG00000030336 and 21940, CD27 and IDBG-640494 and ENSBTAG00000014725 and 512514
• Tissue
  tumor

Gene info

• Identity
  HGNC:11937
• Gene
  CD70
• Long gene name
  CD70 molecule
• Synonyms gene
  • CD27LG
  • TNFSF7
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 7
• Synonyms
  • CD27L
• GenBank acession
  • L08096
• Locus
  19p13.3
• Discovery year
  1993-11-08
• Entrez gene record
  970
• Pubmed identfication
  • 8387892
  • 8120384
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000181834

Gene info

• Identity
  HGNC:43896
• Gene
  CD27-AS1
• Long gene name
  CD27 antisense RNA 1
• Synonyms gene name
  • CD27 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AK056500
• Locus
  12p13.31
• Discovery year
  2012-04-27
• Entrez gene record
  678655
• RefSeq identity
  • NR_015382
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000168315

Gene info

• Identity
  HGNC:11922
• Gene
  CD27
• Long gene name
  CD27 molecule
• Synonyms gene
  • TNFRSF7
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 7
• Synonyms
  • S152
  • Tp55
• GenBank acession
  • M63928
• Locus
  12p13.31
• Discovery year
  1992-06-10
• Entrez gene record
  939
• Pubmed identfication
  • 2442250
  • 8530100
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168316
• Locus Specific Databases
  • LRG_357

Gene info

• Identity
  HGNC:2328
• Gene
  CPT1A
• Long gene name
  carnitine palmitoyltransferase 1A
• Synonyms gene
  • CPT1
• Synonyms gene name
  • carnitine palmitoyltransferase 1A (liver)
• Synonyms
  • CPT1-L
  • L-CPT1
• GenBank acession
  • L39211
• Locus
  11q13.3
• Discovery year
  1995-05-30
• Entrez gene record
  1374
• Pubmed identfication
  • 7892212
  • 9070950
• RefSeq identity
  • NM_001876
• VEGA ID
  OTTHUMG00000167892

Gene info

• Identity
  HGNC:13973
• Gene
  POM121L2
• Long gene name
  POM121 transmembrane nucleoporin like 2
• Synonyms gene name
  • POM121 membrane glycoprotein-like 2 (rat)
  • POM121 membrane glycoprotein-like 2
  • POM121 transmembrane nucleoporin-like 2
• Synonyms
  • POM121-L
• GenBank acession
  • AL021808
• Locus
  6p22.1
• Discovery year
  2001-07-20
• Entrez gene record
  94026
• RefSeq identity
  • NM_033482
• VEGA ID
  OTTHUMG00000014475

Gene info

• Identity
  HGNC:18594
• Gene
  L3MBTL2
• Long gene name
  L3MBTL histone methyl-lysine binding protein 2
• Synonyms gene name
  • l(3)mbt-like 2 (Drosophila)
  • L3MBTL2, polycomb repressive complex 1 subunit
• Synonyms
  • H-l(3)mbt-l
  • DKFZP761I141
  • dJ756G23.3
• GenBank acession
  • AJ305226
• Locus
  22q13.2
• Discovery year
  2002-04-29
• Entrez gene record
  83746
• Pubmed identfication
  • 11682070
  • 21596310
• RefSeq identity
  • NM_031488
• Classification
  • MBT domain containing
• VEGA ID
  OTTHUMG00000150942

Gene info

• Identity
  HGNC:2033
• Gene
  CLDN10
• Long gene name
  claudin 10
• Synonyms
  • OSP-L
  • CPETRL3
• GenBank acession
  • U89916
• Locus
  13q32.1
• Discovery year
  1999-01-22
• Entrez gene record
  9071
• Pubmed identfication
  • 18025272
• RefSeq identity
  • NM_006984
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000017217

Gene info

• Identity
  HGNC:10339
• Gene
  RPL32P1
• Long gene name
  ribosomal protein L32 pseudogene 1
• Synonyms gene
  • RPL32P
• Synonyms gene name
  • ribosomal protein L32 pseudogene
• Synonyms
  • RPL32-L
• GenBank acession
  • X02228
• Locus
  6p21.32
• Discovery year
  2009-03-01
• Entrez gene record
  6163
• Pubmed identfication
  • 3866218
  • 19123937
• RefSeq identity
  • NG_000869
• VEGA ID
  OTTHUMG00000031191

Gene info

• Identity
  HGNC:3555
• Gene
  FABP1
• Long gene name
  fatty acid binding protein 1
• Synonyms gene name
  • fatty acid binding protein 1, liver
• Synonyms
  • L-FABP
• GenBank acession
  • M10617
• Locus
  2p11.2
• Discovery year
  2001-06-22
• Entrez gene record
  2168
• Pubmed identfication
  • 3012800
  • 17698986
• RefSeq identity
  • NM_001443
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000130312

Gene info

• Identity
  HGNC:2288
• Gene
  COX7A2
• Long gene name
  cytochrome c oxidase subunit 7A2
• Synonyms gene name
  • cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
• Synonyms
  • COXVIIa-L
  • COX7AL
• GenBank acession
  • X15822
• Locus
  6q14.1
• Discovery year
  1992-11-25
• Entrez gene record
  1347
• Pubmed identfication
  • 1327965
  • 9202412
• RefSeq identity
  • NM_001865
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000015049

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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