Anti-IL-16 Antibody

• Catalog number
  A1413-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  IL-16
• Target Alternative Name
  Pro-interleukin-16
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IL-16
• Accession
  Q14005
• Gene Id
  3603
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB
• Positive Control
  WB: human blood (A); Jurkat (B) whole cell lysates.
• Application And Usages
  WB; 1:500 – 1:2000
• Description
  Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IL-16  
• Gene symbol
  IL16, ESB3, PIRC88, PIRC83, IFNR, PIRC84
• Short name
  Anti-IL-16 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toIL-16 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5980
• Gene
  IL16
• Long gene name
  interleukin 16
• Synonyms gene name
  • interleukin 16 (lymphocyte chemoattractant factor)
• Synonyms
  • LCF
  • IL-16
  • prIL-16
  • HsT19289
  • FLJ42735
  • FLJ16806
• Synonyms name
  • prointerleukin 16
  • lymphocyte chemoattractant factor
• GenBank acession
  • U82972
• Locus
  15q25.1
• Discovery year
  1997-07-25
• Entrez gene record
  3603
• Pubmed identfication
  • 9144227
• RefSeq identity
  • NM_172217
• Classification
  • Interleukins
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000144186

Gene info

• Identity
  HGNC:3464
• Gene
  ESB3
• Long gene name
  esterase B3
• Locus
  16
• Discovery year
  2001-06-22
• Pubmed identfication
  • 3481956

Gene info

• Identity
  HGNC:37592
• Gene
  PIRC88
• Long gene name
  piwi-interacting RNA cluster 88
• Locus
  16
• Discovery year
  2009-11-05
• Entrez gene record
  100313894
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37587
• Gene
  PIRC83
• Long gene name
  piwi-interacting RNA cluster 83
• Locus
  16
• Discovery year
  2009-11-05
• Entrez gene record
  100313891
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:5447
• Gene
  IFNR
• Long gene name
  interferon production regulator
• Locus
  16
• Discovery year
  1986-01-01
• Entrez gene record
  3466
• Pubmed identfication
  • 1906174
  • 1193239

Gene info

• Identity
  HGNC:37588
• Gene
  PIRC84
• Long gene name
  piwi-interacting RNA cluster 84
• Locus
  16
• Discovery year
  2009-11-05
• Entrez gene record
  100313820
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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