Recombinant Human Serpin B12/SERPINB12 Protein(C-6His)

  • Catalog number
    PKSH033037-10µg
  • Price
    Please ask
  • Size
    10µg
  • Synonym
    SERPINB12;Serpin B12;Serine Protease Inhibitor-clade B12
  • Activity
    NA
  • Sequence
    Met1-Pro425
  • Fusion tag
    C-6His
  • Accession
    P61244
  • Expressed Host
    Human cells
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    >95% as determined by reducing SDS-PAGE.
  • Endotoxin
    <1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass
    49.5 kDa
  • AP Mol Mass
    21 kDa
  • Formulation
    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
  • Background
    Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    SERPINB12, NDUFB3, TNFAIP1
  • Short name
    Recombinant Serpin B12/SERPINB12 Protein(C-6His)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens Serpin B12/SERPINB12 Protein(C-6His)
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    serpin family B member 12
  • Synonyms gene name
    • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12
    • serpin peptidase inhibitor, clade B (ovalbumin), member 12
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-27
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Serpin peptidase inhibitors
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    NADH:ubiquinone oxidoreductase subunit B3
  • Synonyms gene name
    • NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12)
    • NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1997-12-17
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • NADH:ubiquinone oxidoreductase supernumerary subunits
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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