Recombinant Human Serpin B12/SERPINB12 Protein(C-6His)
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Catalog numberPKSH033037-10µg
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PricePlease ask
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Size10µg
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SynonymSERPINB12;Serpin B12;Serine Protease Inhibitor-clade B12
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ActivityNA
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SequenceMet1-Pro425
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Fusion tagC-6His
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AccessionP61244
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Expressed HostHuman cells
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ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity>95% as determined by reducing SDS-PAGE.
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Endotoxin<1.0 EU per µg as determined by LAL test.
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Stability and StorageLyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass49.5 kDa
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AP Mol Mass21 kDa
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FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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BackgroundSerpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolSERPINB12, NDUFB3, TNFAIP1
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Short nameRecombinant Serpin B12/SERPINB12 Protein(C-6His)
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Serpin B12/SERPINB12 Protein(C-6His)
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameserpin family B member 12
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Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12
- serpin peptidase inhibitor, clade B (ovalbumin), member 12
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Serpin peptidase inhibitors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNADH:ubiquinone oxidoreductase subunit B3
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Synonyms gene name
- NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD, B12)
- NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-12-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- NADH:ubiquinone oxidoreductase supernumerary subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF alpha induced protein 1
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor, alpha-induced protein 1 (endothelial)
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Synonyms
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Locus
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Discovery year1991-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BTB domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data