CENTA β-lactamase substrate

Alternative_name

(6R,7R)-3-[(3-carboxy-4-nitrophenyl)sulfanylmethyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Description

CENTA is a chromogenic β-lactamase substrate that is readily hydrolyzed by β-lactamases of all classes except for the Aeromonas hydrophila metalloenzyme. Useful for kinetic studies involving β-lactamases.
CAS Number

9073-60-3
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₁H₁₇N₃O₈S₃
Molecular Weight

535.57
Cell Permeable

Yes
Purity

≥98% by TLC
Solubilities

Phosphate buffer (25 mM) or MeOH
Handling

Protect from light and air
Tag Line

A chromogenic β-lactamase substrate
Storage Condition

-20 ̊C
Shipping Condition

gel pack
Shelf Life

36 months
PubChem CID

133358
PubChem CID Link
SMILES

C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CS3)C(=O)O)CSC4=CC(=C(C=C4)[N+](=O)[O-])C(=O)O
InChi

InChI=1S/C21H17N3O8S3/c25-15(7-11-2-1-5-33-11)22-16-18(26)23-17(21(29)30)10(9-35-19(16)23)8-34-12-3-4-14(24(31)32)13(6-12)20(27)28/h1-6,16,19H,7-9H2,(H,22,25)(H,27,28)(H,29,30)/t16-,19-/m1/s1
InChi Key

PFVWVVUSAORMBB-VQIMIIECSA-N
Data Sheet Link
MSDS Available

Yes