Gossypin
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Catalog number2374-1000
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PricePlease ask
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Size1 g
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Alternative_name3,3',4',5,7,8-Hexahydroxyflavone-8-glucoside
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DescriptionA glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both BRAF-V600E kinase and CDK4 as well as in cells with BRAF wild-type allele. Gossypin inhibits the kinase activities of BRAF-V600E and CDK4, in vitro, possibly through direct binding with these kinases.
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CAS Number652-78-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₀O₁₃
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Molecular Weight480.38
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from light and air
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Tag LineA potent antimelanoma agent
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00017429
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PubChem CID5281621
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SMILESC1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O
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InChiInChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1
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InChi KeySJRXVLUZMMDCNG-KKPQBLLMSA-N
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MSDS AvailableYes
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Gene target
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Short nameGossypin
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Alternative nameGossypin
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