Gossypin

• Catalog number
  2374-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  3,3',4',5,7,8-Hexahydroxyflavone-8-glucoside
• Description
  A glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both BRAF-V600E kinase and CDK4 as well as in cells with BRAF wild-type allele. Gossypin inhibits the kinase activities of BRAF-V600E and CDK4, in vitro, possibly through direct binding with these kinases.
• CAS Number
  652-78-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₀O₁₃
• Molecular Weight
  480.38
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from light and air
• Tag Line
  A potent antimelanoma agent
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00017429
• PubChem CID
  5281621
• PubChem CID Link
• SMILES
  C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O
• InChi
  InChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1
• InChi Key
  SJRXVLUZMMDCNG-KKPQBLLMSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Gossypin  
• Short name
  Gossypin
• Alternative name
  Gossypin

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