ACE2 Inhibitor, DX600

• Catalog number
  9687-1000
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  DX600; Ac-GDYSHCSPLRYYPWWKCTYPDPEGGG-NH2
• Description
  DX600 is a potent ACE2 (Angiotensin-Converting Enzyme 2) inhibitor (Ki = 2.8 nM).
• Structure Available
  No
• Peptide sequence
  Ac - Gly - Asp - Tyr - Ser - His - Cys - Ser - Pro - Leu - Arg - Tyr - Tyr - Pro - Trp - Trp - Lys - Cys - Thr - Tyr - Pro - Asp - Pro - Glu - Gly - Gly - Gly - NH2
• Salt Form
  No
• Molecular Formula
  C₁₄₁H₁₈₇N₃₅O₄₀S₂
• Molecular Weight
  3076.4
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  H₂O (~2 mg/ml)
• Handling
  Protect from moisture
• Tag Line
  a potent ACE2 (Angiotensin-Converting Enzyme 2) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  ACE2   Inhibitor   DX600  
• Gene symbol
  ACE2
• Short name
  ACE2 Inhibitor, DX600
• Alternative name
  angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 suppressor, DX600
• Alternative to gene target
  angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, ACE2 and IDBG-46534 and ENSG00000130234 and 59272, peptide binding, Extracellular, Ace2 and IDBG-184519 and ENSMUSG00000015405 and 70008, ACE2 and IDBG-638902 and ENSBTAG00000034402 and 101908244,509235

Gene info

• Identity
  HGNC:13557
• Gene
  ACE2
• Long gene name
  angiotensin converting enzyme 2
• Synonyms gene name
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
  • angiotensin I converting enzyme 2
• Synonyms
  • ACEH
• Synonyms name
  • peptidyl-dipeptidase A
• GenBank acession
  • AF291820
• Locus
  Xp22.2
• Discovery year
  2000-09-25
• Entrez gene record
  59272
• Pubmed identfication
  • 10969042
• VEGA ID
  OTTHUMG00000021177
• Locus Specific Databases
  • Global Variome shared LOVD

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