Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOXN2
This is a highly specific antibody against FOXN2.
3230402J05Rik; 6030465J18Rik; Fkh19; Forkhead box N2; Forkhead box protein N2; Foxn1; foxn2; FOXN2_HUMAN; HTLF; Human T-cell leukemia virus enhancer factor.
Purified by Protein A.
Human, Mouse, Rat
Gene ID Number
Background of the antigen
The forkhead domain-containing gene family (Fox) comprises over 20 members in mammals and is defined by a conserved 110 amino-acid motif containing a winged helix structure DNA-binding domain. The members of this gene family have been implicated as key regulators of embryogenesis, cell cycling, cell lineage restriction and cancer. As such, FOXN2 contains a domain with homology to the forkhead DNA binding domain. FOXN2, or Human T-cell leukemia virus enhancer factor, is a 341 amino acid protein mapping to human gene FOXN2, which has been localized to human chromosome 2p16-p22. This protein, encoded by a 1239-bp cDNA isolated from the Jurkat cDNA library, is capable of binding to a region of the human T-cell leukemia virus long terminal repeat (HTLV-I LTR) located between amino acids 155 and 117. This purine-rich region is important in the regulation of gene expression by the Ets family of transcription factors. FOXN2 is a unique cellular gene that may function in the transcriptional regulation of HTLV-I LTR.
1ug per 1ul
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.