Carboxypeptidase B, Rat Recombinant

• Catalog number
  P1225-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Carboxypeptidase R, CPR, Carboxypeptidase U, CPU, TAFI
• Alternative_names
  Carboxypeptidase R, CPR, Carboxypeptidase U, CPU, TAFI
• Description
  Catalyzes hydrolysis of the basic amino acids lysine, arginine and histidine
• Recombinant
  Yes
• Source
  Pichia pastoris
• Purity by SDS PAGE
  > 90%
• Assay
  SDS-PAGE
• Activity Specifications test method
  Measured by its ability to hydrolyze one micromole of hippuryl-L-arginine per minute at 25°C, pH-7.65.
• Biological activity
  Specifiv activity ≥170 Units/mg
• Results
  ≥170 Units/mg
• Unit Definition
  One Unit hydrolyzes one micromole of hippuryl-L-arginine per minute at 25°C, pH-7.65.
• Molecular Weight
  34 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Reconstitution Instructions
  Reconstitute the lyophilized Rat Carboxypeptidase B in sterile H2O.
• Background Information
  Carboxypeptidase B (EC 3.4.17.2) catalyzes hydrolysis of the basic amino acids lysine, arginine and ornithine from the C-terminal end of polypeptides. Carboxypeptidase B is inhibited by arginine, lysine and ornithine. The enzyme is not inhibited by di-isopropylfluorophosphate (DFP), but it is inhibited by metal chelating agents, e.g., EDTA, 1,10-phenanthroline.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Carboxypeptidase  
• Gene symbol
  CPM, CPB1, CPB2
• Short name
  Carboxypeptidase B, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Rat
• Species
  Rat, Rats
• Alternative name
  Carboxypeptidase B, Rat Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:2311
• Gene
  CPM
• Long gene name
  carboxypeptidase M
• Synonyms name
  • renal carboxypeptidase
  • urinary carboxypeptidase B
• GenBank acession
  • AF368463
• Locus
  12q15
• Discovery year
  1995-09-11
• Entrez gene record
  1368
• Pubmed identfication
  • 8586455
• RefSeq identity
  • NM_198320
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000169300

Gene info

• Identity
  HGNC:2299
• Gene
  CPB1
• Long gene name
  carboxypeptidase B1
• Synonyms gene name
  • carboxypeptidase B1 (tissue)
• Synonyms name
  • pancreatic carboxypeptidase B
  • tissue carboxypeptidase B
  • protaminase
• GenBank acession
  • AJ224866
• Locus
  3q24
• Discovery year
  1992-04-13
• Entrez gene record
  1360
• RefSeq identity
  • NM_001871
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000159520

Gene info

• Identity
  HGNC:2300
• Gene
  CPB2
• Long gene name
  carboxypeptidase B2
• Synonyms gene name
  • carboxypeptidase B2 (plasma, carboxypeptidase U)
  • carboxypeptidase B2 (plasma)
• Synonyms
  • CPU
  • PCPB
  • TAFI
• Synonyms name
  • thrombin-activatable fibrinolysis inhibitor
  • carboxypeptidase U
  • plasma carboxypeptidase B
  • carboxypeptidase R
• GenBank acession
  • M75106
• Locus
  13q14.13
• Discovery year
  1992-04-10
• Entrez gene record
  1361
• Pubmed identfication
  • 1939207
  • 1427879
• RefSeq identity
  • NM_001872
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000016867
• Locus Specific Databases
  • LRG_632

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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