N-cadherin Antibody, ALEXA FLUOR 647

• Catalog number
  bs-1172R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  N-cadherin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-N-cadherin PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  N-cadherin
• Specificity
  This is a highly specific antibody against N-cadherin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  746-790/906
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human N-cadherin
• Gene ID Number
  1000
• Swiss Prot
  P19022
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  CDHN; NCAD; CD325; CDw325; Cadherin-2; Neural cadherin; N-cadherin; CDH2
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-N-cadherin exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  N-cadherin  
• Gene symbol
  CDH12P2, CDH2, CDH12P1
• Short name
  Anti-N-cadherin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  N-cadherin Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1752
• Gene
  CDH12P2
• Long gene name
  cadherin 12 pseudogene 2
• Synonyms gene
  • CDH12P
• Synonyms gene name
  • cadherin 12 (N-cadherin 2) pseudogene
  • cadherin 12 (N-cadherin 2) pseudogene 2
• Synonyms
  • C41-CAD
• GenBank acession
  • AC004999
• Locus
  5q13.2
• Discovery year
  1995-11-30
• Entrez gene record
  1011
• Pubmed identfication
  • 7731968
  • 10369862
• VEGA ID
  OTTHUMG00000162392

Gene info

• Identity
  HGNC:1759
• Gene
  CDH2
• Long gene name
  cadherin 2
• Synonyms gene
  • NCAD
• Synonyms gene name
  • cadherin 2, type 1, N-cadherin (neuronal)
• Synonyms
  • CDHN
  • CD325
• Synonyms name
  • N-cadherin
• GenBank acession
  • S42303
• Locus
  18q12.1
• Discovery year
  1991-09-13
• Entrez gene record
  1000
• Pubmed identfication
  • 2384753
  • 7731968
  • 2216790
• RefSeq identity
  • NM_001792
• Classification
  • Type I classical cadherins
  • CD molecules
• VEGA ID
  OTTHUMG00000059940

Gene info

• Identity
  HGNC:37698
• Gene
  CDH12P1
• Long gene name
  cadherin 12 pseudogene 1
• Synonyms gene name
  • cadherin 12 (N-cadherin 2) pseudogene 1
• Locus
  5q13.2
• Discovery year
  2010-01-20
• Entrez gene record
  100093625
• RefSeq identity
  • NG_007328.2
• VEGA ID
  OTTHUMG00000164541

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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