Human CellExp™ Glypican 3 / GPC3 Protein, Cynomolgus recombinant

• Catalog number
  P1119-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1
• Alternative_names
  GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1
• Description
  Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 90%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Activity Specifications test method
  Measured by its binding ability in a functional ELISA.
• Biological activity
  Immobilized Human FGF basic, Tag Free at 2ug/mL (100 uL/well) can bind Cynomolgus Glypican 3, Fc Tag with a linear range of 4.8-19.5 ng/mL.
• Binding Capacity
  Immobilized Human FGF basic, Tag Free at 2ug/mL (100 uL/well) can bind Cynomolgus Glypican 3, Fc Tag with a linear range of 4.8-19.5 ng/mL.
• Molecular Weight
  87.5
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   Glypican   GPC3   Protein   Cynomolgus  
• Gene symbol
  GPC3-AS1, GPC3
• Short name
  CellExp™ Glypican 3 / GPC3 Protein, Cynomolgus recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ Glypican 3 / glypican 3 Protein, Cynomolgus Rec.
• Alternative technique
  rec
• Alternative to gene target
  glypican 3, DGSX and GTR2-2 and MXR7 and OCI-5 and SDYS and SGB and SGBS and SGBS1, GPC3 and IDBG-86754 and ENSG00000147257 and 2719, peptidyl-dipeptidase inhibitor activity, Extracellular, Gpc3 and IDBG-145213 and ENSMUSG00000055653 and 14734, GPC3 and IDBG-630953 and ENSBTAG00000020406 and 615239

Gene info

• Identity
  HGNC:52897
• Gene
  GPC3-AS1
• Long gene name
  GPC3 antisense RNA 1
• GenBank acession
  • AF085935
• Locus
  Xq26.2
• Discovery year
  2017-08-04
• Entrez gene record
  110806308
• Pubmed identfication
  • 27573079
  • 31168873
• RefSeq identity
  • NR_148713
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:4451
• Gene
  GPC3
• Long gene name
  glypican 3
• Synonyms gene
  • SDYS
• Synonyms
  • OCI-5
  • SGBS
  • SGBS1
  • SGB
  • DGSX
• Synonyms name
  • glypican proteoglycan 3
• GenBank acession
  • L47125
• Locus
  Xq26.2
• Discovery year
  1996-08-08
• Entrez gene record
  2719
• Pubmed identfication
  • 8589713
  • 9787072
• RefSeq identity
  • NM_004484
• Classification
  • Glypicans
• VEGA ID
  OTTHUMG00000022448
• Locus Specific Databases
  • LRG_505

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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