3,8-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoxaline-d3

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Cas number

1216912-20-7
Chemical s molecular weight

246.24
Chemical s main applications

IQ-type carcinogens found in cooked food are biotransformed and bind to DNA through sequential N2-hydroxylation and O-esterification. The 2-nitro analoges may serve as an intermediate in the chemical synthesis to the metabolites. The metabolites are used in studies with nucleic acids for understanding the molecular aspects of the mutagenic action of these compounds.
Chemical s category

Aromatics, Heterocycles, Isotope Labelled Compounds, Mutagenesis Research Chemicals
Other name

NO2-MeIQx-d3
Chemical s formula

C11H6D3N5O2
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

8-Dimethyl-2-nitro-3H-imidazo[4 5-F]quinoxaline-d3
Gene symbol

IGHV1-69-2, IGHVIII-5-2, DERL2, HLA-F, H3C11, SNAR-F, KLRC4, TRI-AAT5-5, TRG-TCC2-5, TRN-GTT2-5
Short name

3 8-Dimethyl-2-nitro-3H-imidazo[4 5-F]quinoxaline-d3
Alternative name

3,8-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoxaline-d3

Identity

HGNC:5703
Gene

IGHVIII-5-2
Long gene name

immunoglobulin heavy variable (III)-5-2 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (III)-5-2
- immunoglobulin heavy variable (III)-5-2 pseudogene
Synonyms
- IGHV(III)-5-2
GenBank acession
- AB019440
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28353
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152278

Identity

HGNC:4771
Gene

H3C11
Long gene name

H3 clustered histone 11
Synonyms gene
- H3FF
- HIST1H3I
Synonyms gene name
- H3 histone family, member F
- histone 1, H3i
- histone cluster 1, H3i
- histone cluster 1 H3 family member i
Synonyms
- H3/f
- H3.f
GenBank acession
- X83550
Locus

6p22.1
Discovery year

1998-08-27
Entrez gene record

8354
Pubmed identfication
- 9031620
- 9439656
- 12408966
RefSeq identity
- NM_003533
Classification
- H3 histones
VEGA ID

OTTHUMG00000016184

Identity

HGNC:34326
Gene

SNAR-F
Long gene name

small NF90 (ILF3) associated RNA F
Synonyms gene name
- small nuclear ILF3/NF90-associated RNA F
- small ILF3/NF90-associated RNA F
GenBank acession
- EU071073
Locus

19q13.33
Discovery year

2008-06-20
Entrez gene record

100126781
Pubmed identfication
- 17855395
RefSeq identity
- NR_004384
Classification
- Small NF90 (ILF3) associated RNAs

Identity

HGNC:34955
Gene

TRI-AAT5-5
Long gene name

tRNA-Ile (anticodon AAT) 5-5
Synonyms gene
- TRNAI23
- TRI-AAT5-2
Synonyms gene name
- transfer RNA isoleucine 23 (anticodon AAU)
- transfer RNA-Ile (AAT) 5-2
- transfer RNA-Ile (AAT) 5-5
Synonyms
- tRNA-Ile-AAT-5-5
GenBank acession
- HG983848
Locus

17p13.1
Discovery year

2008-08-29
Entrez gene record

100189387
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34598
Gene

TRG-TCC2-5
Long gene name

tRNA-Gly (anticodon TCC) 2-5
Synonyms gene
- TRNAG9
Synonyms gene name
- transfer RNA glycine 9 (anticodon UCC)
- transfer RNA-Gly (TCC) 2-5
Synonyms
- tRNA-Gly-TCC-2-5
GenBank acession
- HG983826
Locus

1q23.3
Discovery year

2008-08-29
Entrez gene record

100189039
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34738
Gene

TRN-GTT2-5
Long gene name

tRNA-Asn (anticodon GTT) 2-5
Synonyms gene
- TRNAN17
Synonyms gene name
- transfer RNA asparagine 17 (anticodon GUU)
- transfer RNA-Asn (GTT) 2-5
Synonyms
- tRNA-Asn-GTT-2-5
GenBank acession
- HG983634
Locus

17q12
Discovery year

2008-08-29
Entrez gene record

100189176
Classification
- Cytoplasmic transfer RNAs