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Also known as
Kappa Light Chain
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Other names
Ig kappa chain V-I region HK101; Ig kappa chain V-I region HK101; N/A; immunoglobulin kappa constant; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
IGKC
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Gene name synonims
N/A
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Other gene names
IGKC; N/A; Km; HCAK1; IGKCD; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1, kappa
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Clone
L1C1
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens). Does not react with Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
N/A
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Concentration
N/A
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Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applications
ELISA (EIA), Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
