Hesperadin

• Catalog number
  B1940-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-[(3Z)-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide
• Description
  Hesperadin is a potent, ATP-competitive inhibitor of Aurora B kinase (IC₅₀ = 250 nM). Hesperadin inhibits Aurora B kinase by phosphorylation of histone H3. Also acts as a broad-spectrum influenza antiviral agent.
• CAS Number
  422513-13-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₉H₃₂N₄O₃S
• Molecular Weight
  516.65
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, ATP-competitive inhibitor of Aurora B kinase
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  10142586
• PubChem CID Link
• SMILES
  CCS(=O)(=O)NC1=CC2=C(C=C1)NC(=O)C2=C(C3=CC=CC=C3)NC4=CC=C(C=C4)CN5CCCCC5
• InChi
  InChI=1S/C29H32N4O3S/c1-2-37(35,36)32-24-15-16-26-25(19-24)27(29(34)31-26)28(22-9-5-3-6-10-22)30-23-13-11-21(12-14-23)20-33-17-7-4-8-18-33/h3,5-6,9-16,19,30,32H,2,4,7-8,17-18,20H2,1H3,(H,31,34)/b28-27-
• InChi Key
  GLDSKRNGVVYJAB-DQSJHHFOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Hesperadin  
• Short name
  Hesperadin
• Alternative name
  Hesperadin

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