Cathepsin L Antibody

• Catalog number
  3192-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Cathepsin L
• Target Alternative Name
  CTSL, CATL, CTSL1, MEP, EC 3.4.22.15
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 223 of human Cathepsin L
• Accession
  P07711
• Gene Id
  1514
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) affinity purified rabbit anti-cathepsin L polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.1% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Positive Control
  Western Blot: Jurkat cell lysate. IHC: Kidney tissue
• Application And Usages
  Western blotting (0.5-4 µg/ml), and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control. Detects both the proenzyme and the mature form of cathepsin L
• Description
  Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid pro-peptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins sμggests that it may play a role in invasion and metastasis and could be a useful prognostic indicator for cancer.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
• French translation
  anticorps

• Gene target
  Cathepsin  
• Gene symbol
  CTSLP2, CTSL3P, CTSLP3
• Short name
  Cathepsin L Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Cathepsin L (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2540
• Gene
  CTSLP2
• Long gene name
  cathepsin L pseudogene 2
• Synonyms gene
  • CTSLL2
  • CTSL1P2
  • CTSLP5
  • CTSLL5
  • CTSL1P5
  • CTSLP7
  • CTSLL7
  • CTSL1P7
• Synonyms gene name
  • cathepsin L-like 2
  • cathepsin L1 pseudogene 2
  • cathepsin L pseudogene 5
  • cathepsin L-like 5
  • cathepsin L1 pseudogene 5
  • cathepsin L pseudogene 7
  • cathepsin L-like 7
  • cathepsin L1 pseudogene 7
• Synonyms
  • bA342C24.4
  • bA144G6.6
• GenBank acession
  • L25628
• Locus
  10q11.22
• Discovery year
  1993-12-06
• Entrez gene record
  1517
• Pubmed identfication
  • 7713509
• RefSeq identity
  • NR_033407
• VEGA ID
  OTTHUMG00000018112

Gene info

• Identity
  HGNC:33132
• Gene
  CTSL3P
• Long gene name
  cathepsin L family member 3, pseudogene
• Synonyms gene
  • CTSL3
• Synonyms gene name
  • cathepsin L family member 3
• Synonyms
  • HCTSL-s
• GenBank acession
  • AJ851862
• Locus
  9q21.33
• Discovery year
  2007-04-27
• Entrez gene record
  392360
• Pubmed identfication
  • 19663681
• RefSeq identity
  • NR_027917
• VEGA ID
  OTTHUMG00000020152

Gene info

• Identity
  HGNC:2541
• Gene
  CTSLP3
• Long gene name
  cathepsin L pseudogene 3
• Synonyms gene
  • CTSLL3
  • CTSL1P3
• Synonyms gene name
  • cathepsin L-like 3
  • cathepsin L1 pseudogene 3
• GenBank acession
  • L25629
• Locus
  10q11.22
• Discovery year
  1993-12-06
• Entrez gene record
  644021
• Pubmed identfication
  • 7713509
• RefSeq identity
  • NG_016830

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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