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Alternative_name
N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-2-yl]-2-(tert-butylamino)acetamide
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Description
A glycylglycine type of antibiotic derived from tetracycline. Inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecules into the A site of the ribosome. This prevents incorporation of amino acid residues into elongating peptide chains.
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CAS Number
220620-09-7
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₉H₃₉N₅O₈
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Molecular Weight
586.65
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO (~ 3 mg/ml with warming)
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Handling
Protect from air and moisture
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Tag Line
A protein translocation inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
48 months
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MDL Number
MFCD00935753
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PubChem CID
54686904
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SMILES
CC(C)(C)NCC(=O)NC1=C(C2=C(CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C2O)O)O)C(=O)N)N (C)C)C(=C1)N(C)C)O
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InChi
InChI=1S/C29H39N5O8/c1-28(2, 3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30) 41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31, 36-37,40,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
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InChi Key
SOVUOXKZCCAWOJ-HJYUBDRYSA-N
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MSDS Available
Yes