Ertugliflozin

  • Catalog number
    B1896-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-hydroxymethyl-6,8-dioxabicyclo(3.2.1)octane-2,3,4-triol; PF-04971729
  • Description
    Ertugliflozin is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2); increases the excretion of glucose with a 2,000-fold selectivity over SGLT1 (IC₅₀ = 0.877 and 1,960 nM, respectively, for human isoforms in vitro.
  • CAS Number
    1210344-57-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₂₅ClO₇
  • Molecular Weight
    436.89
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective sodium-dependent glucose cotransporter 2(SGLT2) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    44814423
  • SMILES
    CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl
  • InChi
    InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22-/m0/s1
  • InChi Key
    MCIACXAZCBVDEE-CUUWFGFTSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Ertugliflozin
  • Alternative name
    Ertugliflozin
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