FXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4)
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Catalog numberGEN603991
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PricePlease ask
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Size100ug
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Also known asFXR
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Other namesFXR; FXR; farnesoid X-activated receptor; farnesoid X-activated receptor; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene namefxr; fxr; fxr; N/A
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Gene name synonimsfxr; fxr; fxr; N/A
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Other gene namesfxr; fxr; fxr; N/A
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2a
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Clone5L1
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human FXR. Species Crossreactivity: rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodPurified by ammonium sulfate precipitation.
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Form AppearanceSupplied as a liquid in PBS, 0.1% sodium azide.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolNR1H4, BFAR, ADRB2, AP1AR, GPBAR1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
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Short nameFXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4)
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Alternative nameAnti-FXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4)
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Alternative to gene targetnuclear receptor subfamily 1, group H, member 4, BAR and FXR and HRR-1 and HRR1 and RIP14, NR1H4 and IDBG-52872 and ENSG00000012504 and 9971, chenodeoxycholic acid binding, nuclei, Nr1h4 and IDBG-184281 and ENSMUSG00000047638 and 20186, BT.48865 and IDBG-636894 and ENSBTAG00000013596 and 540528
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Gene info
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Identity
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Gene
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Long gene namenuclear receptor subfamily 1 group H member 4
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Synonyms gene name
- nuclear receptor subfamily 1, group H, member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nuclear receptor subfamily 1 group H
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebifunctional apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sterile alpha motif domain containing
- Ring finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadrenoceptor beta 2
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Synonyms gene
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Synonyms gene name
- adrenergic, beta-2-, receptor, surface
- adrenoceptor beta 2, surface
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-09-10
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Entrez gene record
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RefSeq identity
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Classification
- Adrenoceptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadaptor related protein complex 1 associated regulatory protein
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Synonyms gene
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Synonyms gene name
- chromosome 4 open reading frame 16
- adaptor-related protein complex 1 associated regulatory protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-09-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled bile acid receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-01-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled bile acid receptor
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
