Recombinant Human MKK6 / MEK6 / MAP2K6 Protein (His & GST tag) 50µg
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Catalog number
PKSH030415-50µg
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Price
Please ask
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Size
50µg
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Synonym
MAPKK6;MEK6;MKK6;PRKMK6;SAPKK-3;SAPKK3
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Activity
NA
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Sequence
Met 1-Asp 334
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Fusion tag
N-His & GST
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Accession
P52564-1
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Expressed Host
Baculovirus-Insect Cells
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Shipping
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.Shipment made at ambient temperature may seriously affect the activity of the ordered products.
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Purity
＞80 % as determined by SDS-PAGE
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Endotoxin
＜1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
65.3 kDa
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AP Mol Mass
60 kDa
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Formulation
Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0
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Reconstitution
Please refer to it for detailed information.
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Background
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6 and MKK6, is a protein which belongs to the?protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one?protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
MAP2K6, MGST3
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Short name
Recombinant MKK6 / MEK6 / MAP2K6 Protein (His & GST tag) 50µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens MKK6 / MEK6 / mitogen-activated protein kinase kinase 6 Protein (histidine & GST detection labelled) 50µg
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Alternative technique
rec
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Alternative to gene target
mitogen-activated protein kinase kinase 6, MAPKK6 and MEK6 and MKK6 and PRKMK6 and SAPKK-3 and SAPKK3, MAP2K6 and IDBG-66516 and ENSG00000108984 and 5608, transferase activity, nuclei, Map2k6 and IDBG-213977 and ENSMUSG00000020623 and 26399, MAP2K6 and IDBG-643571 and ENSBTAG00000001609 and 100849300,286883
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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