UNC2881

• Catalog number
  2837-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-(4-(1H-imidazol-1-yl)benzyl)-2-(butylamino)-4-(((1r,4r)-4-hydroxycyclohexyl)amino)pyrimidine-5-carboxamide
• Description
  UNC2881 is a potent Mer kinase inhibitor. It inhibits steady-state Mer kinase phosphorylation with an IC₅₀ value of 22 nM. Treatment with UNC2281 is also sufficient to block EGF-mediated stimulation of a chimeric receptor containing the intracellular domain of Mer fused to the extracellular domain of EGFR.
• CAS Number
  1493764-08-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₃₃N₇O₂
• Molecular Weight
  463.58
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent Mer kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  71721525
• PubChem CID Link
• SMILES
  CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4
• InChi
  InChI=1S/C25H33N7O2/c1-2-3-12-27-25-29-16-22(23(31-25)30-19-6-10-21(33)11-7-19)24(34)28-15-18-4-8-20(9-5-18)32-14-13-26-17-32/h4-5,8-9,13-14,16-17,19,21,33H,2-3,6-7,10-12,15H2,1H3,(H,28,34)(H2,27,29,30,31)
• InChi Key
  NPVXOWLPOFYACO-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  UNC2881  
• Short name
  UNC2881
• Alternative name
  UNC2881

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