LY-83583

• Catalog number
  B1314-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  6-(phenylamino)-5,8-quinolinedione
• Description
  LY-83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC₅₀ value of 2 µM. Also blocks the release of intracellular Ca²⁺ and antigen-induced leukotrienes.
• CAS Number
  91300-60-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₀N₂O₂
• Molecular Weight
  250.25
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An inhibitor of soluble guanylate cyclase and of cGMP production
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00210756
• PubChem CID
  3976
• PubChem CID Link
• SMILES
  C1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)C=CC=N3
• InChi
  InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
• InChi Key
  GXIJYWUWLNHKNW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  LY-83583  
• Gene symbol
  ARHGDIB
• Short name
  LY-83583
• Alternative name
  LY-83583

Gene info

• Identity
  HGNC:679
• Gene
  ARHGDIB
• Long gene name
  Rho GDP dissociation inhibitor beta
• Synonyms gene
  • RAP1GN1
  • GDIA2
  • GDID4
• Synonyms gene name
  • Rho GDP dissociation inhibitor (GDI) beta
• Synonyms
  • Ly-GDI
  • RhoGDI2
• GenBank acession
  • L07916
• Locus
  12p12.3
• Discovery year
  1994-08-29
• Entrez gene record
  397
• Pubmed identfication
  • 8434008
  • 8356058
• RefSeq identity
  • NM_001175
• Classification
  • Receptor ligands
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000168742

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