Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 Protein(C-6His) 50µg

• Catalog number
  PKSH033133-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  CD320 antigen;8D6 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;Transcobalamin receptor;TCblR;CD320
• Activity
  NA
• Sequence
  Ser36-Val231
• Fusion tag
  C-6His
• Accession
  Q9NPF0
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  21.1 kDa
• AP Mol Mass
  43 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 10mM Tris-Citrate,150mM NaCl, pH 7.4.
• Reconstitution
  Please refer to it for detailed information.
• Background
  CD320 antigen is also known as 8D6 antigen，FDC-signaling molecule 8D6，Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Transcobalamin   Receptor/TCblR/8D6A/CD320   Protein   C-6His   50µg  
• Gene symbol
  CD320
• Short name
  Recombinant Transcobalamin II Receptor/TCblR/8D6A/CD320 Protein(C-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Transcobalamin II Receptor/TCblR/8D6A/CD320 molecule Protein(C-6His) 50µg
• Alternative technique
  rec
• Alternative to gene target
  CD320 molecule, CD320 and IDBG-24538 and ENSG00000167775 and 51293, cobalamin binding, Plasma membranes, Cd320 and IDBG-168060 and ENSMUSG00000002308 and 54219, CD320 and IDBG-643810 and ENSBTAG00000004403 and 505043

Gene info

• Identity
  HGNC:16692
• Gene
  CD320
• Long gene name
  CD320 molecule
• Synonyms gene name
  • CD320 antigen
• Synonyms
  • 8D6
  • 8D6A
• Synonyms name
  • 8D6 antigen
• GenBank acession
  • AF161254
• Locus
  19p13.2
• Discovery year
  2005-02-09
• Entrez gene record
  51293
• Pubmed identfication
  • 10727470
• RefSeq identity
  • NM_016579
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000182457

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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