Thy1/CD90 Antibody (NT)

  • Catalog number
    6778-100
  • Price
    Please ask
  • Size
    100 μl
  • Antibody Target
    Thy1/CD90
  • Target Alternative Name
    THY1; Thy-1 membrane glycoprotein; CDw90; Thy-1 antigen; CD90
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Rat.
  • Immunogen Sequence
    This THY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human THY1.
  • Accession
    7070
  • Gene Id
    P04216
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In PBS with 0.09% (W/V) sodium azide.
  • Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • Application
    Western blot, IHC.
  • Positive Control
    Western blot: T47D, HL60 cell lysate, IHC: human hepatocarcinoma and cancer tissue .
  • Application And Usages
    WB: 1:1000, IHC: 1:50 – 1:100.
  • Description
    Thy1 is a GPI-anchored, developmentally regulated protein involved in various signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosis. It is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migratory events, such as neurite extension. Decreased Thy1 expression is associated with the development of epithelial ovarian cancer, revealing its role as a putative tumor suppressor gene of human ovarian cancer. Thy1 knockout mice have impaired cutaneous immune responses and abnormal retinal development. Thy1 is epigenetically regulated or deregulated in some disease states, such as pulmonary fibrosis. The potentially reversible hypermethylation of the Thy1 promoter offers the possibility of novel therapeutic options in this disease.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    THY1
  • Short name
    Thy1/CD90 Antibody (NT)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Thy-1 cellular surface antigen/CD90 (antibody to-) (NT)
  • Alternative technique
    antibodies
  • Alternative to gene target
    Thy-1 cell surface antigen, CD90, THY1 and IDBG-74502 and ENSG00000154096 and 7070, GPI anchor binding, Cell surfaces, Thy1 and IDBG-155394 and ENSMUSG00000032011 and 21838, THY1 and IDBG-631960 and ENSBTAG00000019627 and 614712
Gene info
  • Identity
  • Gene
  • Long gene name
    Thy-1 cell surface antigen
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Immunoglobulin like domain containing
    • Ig-like cell adhesion molecule family
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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