Thy1/CD90 Antibody (NT)
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Catalog number6778-100
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PricePlease ask
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Size100 μl
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Antibody TargetThy1/CD90
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Target Alternative NameTHY1; Thy-1 membrane glycoprotein; CDw90; Thy-1 antigen; CD90
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Antibody TypePolyclonal
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Species ReactivitiesHuman, Rat.
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Immunogen SequenceThis THY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human THY1.
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Accession7070
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Gene IdP04216
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS with 0.09% (W/V) sodium azide.
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PurificationThis antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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ApplicationWestern blot, IHC.
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Positive ControlWestern blot: T47D, HL60 cell lysate, IHC: human hepatocarcinoma and cancer tissue .
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Application And UsagesWB: 1:1000, IHC: 1:50 – 1:100.
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DescriptionThy1 is a GPI-anchored, developmentally regulated protein involved in various signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosis. It is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migratory events, such as neurite extension. Decreased Thy1 expression is associated with the development of epithelial ovarian cancer, revealing its role as a putative tumor suppressor gene of human ovarian cancer. Thy1 knockout mice have impaired cutaneous immune responses and abnormal retinal development. Thy1 is epigenetically regulated or deregulated in some disease states, such as pulmonary fibrosis. The potentially reversible hypermethylation of the Thy1 promoter offers the possibility of novel therapeutic options in this disease.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTHY1
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Short nameThy1/CD90 Antibody (NT)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameThy-1 cellular surface antigen/CD90 (antibody to-) (NT)
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Alternative techniqueantibodies
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Alternative to gene targetThy-1 cell surface antigen, CD90, THY1 and IDBG-74502 and ENSG00000154096 and 7070, GPI anchor binding, Cell surfaces, Thy1 and IDBG-155394 and ENSMUSG00000032011 and 21838, THY1 and IDBG-631960 and ENSBTAG00000019627 and 614712
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Gene info
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Identity
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Gene
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Long gene nameThy-1 cell surface antigen
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- Ig-like cell adhesion molecule family
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data